Associate Scientist I
Company: Lumen Bioscience
Location: Seattle
Posted on: October 8, 2024
Job Description:
Summary:The Associate Scientist will work with and support
scientists in the Biologics research and development team. The work
will focus on designing, validating, characterizing, and conducting
a wide range of microbial and bacterial assays to support Lumen's
therapeutic objectives. The candidate will play a key role in
microbiology, molecular biology, and microscopy tasks, such as
immunofluorescent microscopy, culturing BSL-2 microorganisms, and
performing tissue-culture models of bacterial infection. Experience
with bioinformatics tools, particularly Biopython, would be a
plus.The individual is also expected to independently perform and
learn new laboratory techniques, use specialized laboratory
instruments, perform delicate manual procedures, follow and apply
standard laboratory protocols and procedures, record, analyze, and
report results, and provide reliable, independent, and versatile
support to biotechnology research.The position requires strong
organizational skills and meticulous laboratory record keeping.
Effective communication skills are crucial in coordinating with
Lumen's research and production scientists, providing status
updates, and raising quality or troubleshooting issues as they may
arise.Essential Duties and Responsibilities:The major tasks for
this position are as follows:
- Development and optimization of microbial and bacterial assays
to assess therapeutic candidates.
- Performing tissue-culture models of bacterial infection and
working with BSL-2 microorganisms.
- Screening large sets of molecules across various microbial
panels using dPCR, immunofluorescence-based microscopy, and MIC
assays.
- Following established protocols for a wide range of
microbiology, molecular biology, and protein biochemistry
assays.
- Developing and optimizing new protocols as needed.
- Handling, tracking, and safely managing BSL-2 materials.
- Integrating new tools and techniques to expand assay
capabilities.
- Utilizing bioinformatics tools, particularly Biopython, for
sequence analysis and data interpretation is preferred but not
required.
- All lab staff are expected to dedicate 10% of their time to
supporting lab operations (maintenance, clean-up, etc.).*This job
description is not designed to cover or contain a comprehensive
listing of duties, activities, or responsibilities that are
required of the employee. Other duties, responsibilities, and
activities may change or be assigned at any time with or without
notice.Desired Qualifications & Requirements:
- BA/BS degree in microbiology, cell biology, biochemistry,
biotechnology, or related field of study with 2-5 years' laboratory
experience.
- MS/MSc degree in microbiology, cell biology, biochemistry,
biotechnology, or related field of study with 0-2 years' laboratory
experience.Successful candidate will have the following
attributes:
- Proficient in handling and tracking BSL-2 microorganisms.
- Skilled in microbial and bacterial assay development,
optimization, and validation.
- Strong background in molecular biology, including expertise in
DNA isolation, qPCR or dPCR.
- Competence in tissue culture growth of mammalian cells.
- Knowledgeable in immunofluorescence microscopy.
- Experience with bioinformatics tools, particularly Biopython,
is a bonus but not required.
- Strong attention to detail and organizational skills.
- Engage with members of the team in experimental design,
troubleshooting, data analysis, and data interpretation.
- Self-starter, able to contribute effectively in a fast-changing
environment.
- The ability to work both independently and in a team-oriented
environment.
- High integrity and ethics.
- Commitment to quality and timely delivery of results.
- Respect laboratory safety policies and practices.Physical
Requirements:
- Sit for extended periods of time (2 or more hours).
- The position also requires standing on your feet for extended
periods of time.
- Occasionally lift or carry up to 50 lbs. with assistance.
- Perform delicate manual procedures in the laboratory.This is a
full-time position with a salary range of $80,000 to $85,000 +
stock bonus. The base salary range represents the anticipated low
and high end of the salary range for this position. Individual
placement within a salary range will vary based upon factors
including but not limited to a candidate's skillset, experience,
knowledge, education, and performance.
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Keywords: Lumen Bioscience, Federal Way , Associate Scientist I, Other , Seattle, Washington
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